POLH Antikörper (AA 408-609)

Produktnummer ABIN7150247

Produktdetails anti-POLH Antikörper

Target: POLH (Polymerase (DNA Directed), eta (POLH))

Bindungsspezifität: AA 408-609

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA polymerase eta protein (408-609AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POLH

Target: POLH (Polymerase (DNA Directed), eta (POLH))

Andere Bezeichnung: POLH (POLH Produkte)

Synonyme: POLH antikoerper, fc50a12 antikoerper, wu:fc50a12 antikoerper, zgc:136881 antikoerper, zgc:152642 antikoerper, RAD30 antikoerper, RAD30A antikoerper, XP-V antikoerper, XPV antikoerper, polymerase (DNA directed), eta S homeolog antikoerper, DNA polymerase eta antikoerper, polymerase (DNA directed), eta antikoerper, putative DNA polymerase eta antikoerper, polymerase (DNA directed), eta (RAD 30 related) antikoerper, polh.S antikoerper, POLH antikoerper, polh antikoerper, Tb10.70.6190 antikoerper, LINJ_21_0690 antikoerper, Polh antikoerper, LOC100443019 antikoerper

Hintergrund:

Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5\\\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

Aliases: DNA polymerase eta antibody, FLJ16395 antibody, FLJ21978 antibody, Polh antibody, POLH_HUMAN antibody, polymerase DNA directed eta antibody, RAD30 antibody, RAD30 homolog A antibody, RAD30A antibody, Xeroderma pigmentosum variant type protein antibody, XP V antibody, XPV antibody

UniProt: Q9Y253

Pathways: DNA Reparatur