POLH Antikörper (AA 408-609) (HRP)
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- Target Alle POLH Antikörper anzeigen
- POLH (Polymerase (DNA Directed), eta (POLH))
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Bindungsspezifität
- AA 408-609
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLH Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human DNA polymerase eta protein (408-609AA)
- Isotyp
- IgG
- Top Product
- Discover our top product POLH Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- POLH (Polymerase (DNA Directed), eta (POLH))
- Andere Bezeichnung
- POLH (POLH Produkte)
- Hintergrund
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Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
Aliases: DNA polymerase eta antibody, FLJ16395 antibody, FLJ21978 antibody, Polh antibody, POLH_HUMAN antibody, polymerase DNA directed eta antibody, RAD30 antibody, RAD30 homolog A antibody, RAD30A antibody, Xeroderma pigmentosum variant type protein antibody, XP V antibody, XPV antibody
- UniProt
- Q9Y253
- Pathways
- DNA Reparatur
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