SATB2 Antikörper (AA 228-369)

Produktnummer ABIN7150394

Produktdetails anti-SATB2 Antikörper

Target: SATB2 (SATB Homeobox 2 (SATB2))

Bindungsspezifität: AA 228-369

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SATB2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human DNA-binding protein SATB2 protein (228-369AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SATB2

Target: SATB2 (SATB Homeobox 2 (SATB2))

Andere Bezeichnung: SATB2 (SATB2 Produkte)

Synonyme: RGD1562369 antikoerper, mKIAA1034 antikoerper, SATB homeobox 2 antikoerper, special AT-rich sequence binding protein 2 antikoerper, SATB2 antikoerper, satb2 antikoerper, Satb2 antikoerper

Hintergrund:

Background: Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.

Aliases: DNA binding protein SATB2 antibody, DNA-binding protein SATB2 antibody, FLJ21474 antibody, FLJ32076 antibody, GLSS antibody, KIAA1034 antibody, MGC119474 antibody, MGC119477 antibody, SATB family member 2 antibody, SATB homeobox 2 antibody, SATB2 antibody, SATB2_HUMAN antibody, Special AT rich sequence binding protein 2 antibody, Special AT-rich sequence-binding protein 2 antibody

UniProt: Q9UPW6