POLR2D Antikörper (AA 1-142) (Biotin)

Produktnummer ABIN7150435

Produktdetails anti-POLR2D Antikörper (Biotin)

Target: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Bindungsspezifität: AA 1-142

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2D Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed RNA polymerase II subunit RPB4 protein (1-142AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POLR2D

Target: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Andere Bezeichnung: POLR2D (POLR2D Produkte)

Synonyme: wu:fa95b11 antikoerper, zgc:110435 antikoerper, HSRBP4 antikoerper, HSRPB4 antikoerper, RBP4 antikoerper, RPB16 antikoerper, 2310002G05Rik antikoerper, 2610028L19Rik antikoerper, RNA polymerase II subunit D antikoerper, DNA-directed RNA polymerase II 16 kDa polypeptide antikoerper, polymerase (RNA) II (DNA directed) polypeptide D antikoerper, Polr2d antikoerper, CpipJ_CPIJ006734 antikoerper, UREG_01395 antikoerper, LOC100282338 antikoerper, polr2d antikoerper, POLR2D antikoerper

Hintergrund:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.

Aliases: DNA directed RNA polymerase II 16 kDa polypeptide antibody, DNA directed RNA polymerase II subunit D antibody, DNA directed RNA polymerase II subunit RPB4 antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, DNA-directed RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II subunit rpb4 antibody, HSRBP4 antibody, HSRPB4 antibody, polr2d antibody, polymerase RNA II DNA directed polypeptide D antibody, RBP4 antibody, RNA polymerase II 16 kDa subunit antibody, RNA polymerase II subunit B4 antibody, RNA polymerase II subunit D antibody, RNA polymerase II subunit hsRBP4 antibody, RPB16 antibody, RPB4_HUMAN antibody

UniProt: O15514

Pathways: Regulatorische RNA Pathways