DAD1 Antikörper (AA 1-113) (Biotin)

Produktnummer ABIN7150600

Produktdetails anti-DAD1 Antikörper (Biotin)

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Bindungsspezifität: AA 1-113

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAD1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein (1-113AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DAD1

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Andere Bezeichnung: DAD1 (DAD1 Produkte)

Synonyme: NV18456 antikoerper, dad1 antikoerper, DAD1 antikoerper, ost2 antikoerper, DAD-1 antikoerper, si:ch211-9d9.5 antikoerper, OST2 antikoerper, AI323713 antikoerper, DEFENDER AGAINST APOPTOTIC DEATH 1 antikoerper, F3C3.14 antikoerper, F3C3_14 antikoerper, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antikoerper, defender against cell death 1 antikoerper, hypothetical protein antikoerper, defender against cell death 1 S homeolog antikoerper, Defender against death (DAD family) protein antikoerper, false DAD1 antikoerper, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 antikoerper, LOC100115214 antikoerper, DAD1 antikoerper, dad1 antikoerper, CC1G_00458 antikoerper, CpipJ_CPIJ003512 antikoerper, PGTG_09898 antikoerper, Dad1 antikoerper, dad1.S antikoerper, ATDAD1 antikoerper, fdad1 antikoerper, dad-1 antikoerper

Hintergrund:

Background: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:22467853). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes. Loss of the DAD1 protein triggers apoptosis (PubMed:22467853).

Aliases: DAD 1 antibody, DAD-1 antibody, dad1 antibody, DAD1_HUMAN antibody, Defender against cell death 1 antibody, Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, Oligosaccharyl transferase subunit DAD1 antibody, OST 2 antibody, OST2 antibody

UniProt: P61803