DSCAM Antikörper (AA 1711-1867)

Produktnummer ABIN7150649

Produktdetails anti-DSCAM Antikörper

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Bindungsspezifität: AA 1711-1867

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DSCAM Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Down syndrome cell adhesion molecule protein (1711-1867AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DSCAM

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Andere Bezeichnung: DSCAM (DSCAM Produkte)

Synonyme: CHD2-42 antikoerper, CHD2-52 antikoerper, Dscam antikoerper, DSCAM antikoerper, chd2-42 antikoerper, chd2-52 antikoerper, dscam antikoerper, GB15141 antikoerper, 4932410A21Rik antikoerper, 43Bc antikoerper, CG17800 antikoerper, CT39257 antikoerper, DScam antikoerper, DmDscam antikoerper, Dm_2R:13612 antikoerper, Dmel\\CG17800 antikoerper, Dscam-hv antikoerper, Dscam1 antikoerper, FBgn0033159 antikoerper, Neu1 antikoerper, dScam antikoerper, l(2)05518 antikoerper, l(2)43Bc antikoerper, p270 antikoerper, DS cell adhesion molecule antikoerper, Down syndrome cell adhesion molecule antikoerper, Down syndrome cell adhesion molecule a antikoerper, Down syndrome cell adhesion molecule 1 antikoerper, Down syndrome cell adhesion molecule-like protein Dscam2 antikoerper, down syndrome cell adhesion molecule antikoerper, Down syndrome cell adhesion molecule L homeolog antikoerper, DSCAM antikoerper, Dscam antikoerper, dscam antikoerper, dscama antikoerper, Dscam1 antikoerper, LOC5573626 antikoerper, CpipJ_CPIJ006173 antikoerper, dscam.L antikoerper

Hintergrund:

Background: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed:15169762). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).

Aliases: CHD2 42 antibody, CHD2 52 antibody, CHD2 antibody, Down syndrome cell adhesion molecule antibody, DSCAM antibody, DSCAM_HUMAN antibody, human CHD2-52 down syndrome cell adhesion molecule 2, 9 antibody, OTTHUMP00000109193 2 antibody, SD11109p antibody

UniProt: O60469

Pathways: Regulation of Cell Size