DTNBP1 Antikörper (AA 258-351) (HRP)
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- Target Alle DTNBP1 Antikörper anzeigen
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
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Bindungsspezifität
- AA 258-351
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DTNBP1 Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Dysbindin protein (258-351AA)
- Isotyp
- IgG
- Top Product
- Discover our top product DTNBP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
- Andere Bezeichnung
- DTNBP1 (DTNBP1 Produkte)
- Synonyme
- 5430437B18Rik antikoerper, AW048963 antikoerper, Bloc1s8 antikoerper, dysbindin antikoerper, sdy antikoerper, BLOC1S8 antikoerper, DBND antikoerper, HPS7 antikoerper, My031 antikoerper, SDY antikoerper, dtnbp1 antikoerper, zgc:56462 antikoerper, MGC83903 antikoerper, dbnd antikoerper, hps7 antikoerper, my031 antikoerper, MGC85477 antikoerper, DTNBP1 antikoerper, CG6856 antikoerper, Ddysb antikoerper, Dmel\\CG6856 antikoerper, si:ch211-285p6.1 antikoerper, dystrobrevin binding protein 1 antikoerper, Dysbindin antikoerper, dystrobrevin binding protein 1a antikoerper, dystrobrevin binding protein 1 L homeolog antikoerper, dystrobrevin binding protein 1 S homeolog antikoerper, dystrobrevin binding protein 1b antikoerper, Dtnbp1 antikoerper, DTNBP1 antikoerper, dtbp1 antikoerper, dtnbp1a antikoerper, dtnbp1.L antikoerper, dtnbp1.S antikoerper, dtnbp1 antikoerper, Dysb antikoerper, dtnbp1b antikoerper
- Hintergrund
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Background: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
Aliases: DTBP1_HUMAN antibody, DTNBP1 antibody, Dysbindin antibody, Dysbindin-1 antibody, Dystrobrevin binding protein 1 antibody, Dystrobrevin-binding protein 1 antibody, Hermansky Pudlak syndrome 7 protein antibody, Hermansky-Pudlak syndrome 7 protein antibody, HPS7 antibody, HPS7 protein antibody
- UniProt
- Q96EV8
- Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
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