MSL2 Antikörper (AA 341-473) (Biotin)

Produktnummer ABIN7151073

Produktdetails anti-MSL2 Antikörper (Biotin)

Target: MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

Bindungsspezifität: AA 341-473

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSL2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase MSL2 protein (341-473AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MSL2

Target: MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

Andere Bezeichnung: MSL2 (MSL2 Produkte)

Synonyme: MSL-2 antikoerper, MSL2L1 antikoerper, RNF184 antikoerper, E130103E02Rik antikoerper, Msl2l1 antikoerper, Rnf184 antikoerper, RGD1310355 antikoerper, MSL complex subunit 2 antikoerper, male-specific lethal 2 homolog (Drosophila) antikoerper, MSL2 antikoerper, Msl2 antikoerper

Hintergrund:

Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at \'Lys-35\' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at \'Lys-4\' (H3K4me) and \'Lys-79\' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.

Aliases: Male specific lethal 2 homolog (Drosophila) antibody, Male specific lethal 2 homolog 1 antibody, Male specific lethal 2 homolog antibody, Male specific lethal 2 like 1 antibody, Male-specific lethal 2 homolog antibody, Male-specific lethal 2-like 1 antibody, Male-specific lethal-2 homolog 1 antibody, MSL-2 antibody, MSL2 antibody, MSL2-like 1 antibody, MSL2_HUMAN antibody, MSL2L1 antibody, Ring finger protein 184 antibody

UniProt: Q9HCI7