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RNF128 Antikörper (AA 229-400) (HRP)

RNF128 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7151141
  • Target Alle RNF128 Antikörper anzeigen
    RNF128 (Ring Finger Protein 128 (RNF128))
    Bindungsspezifität
    • 7
    • 5
    • 4
    • 2
    • 1
    AA 229-400
    Reaktivität
    • 35
    • 21
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Human
    Wirt
    • 35
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF128 Antikörper ist konjugiert mit HRP
    Applikation
    • 31
    • 13
    • 11
    • 4
    • 2
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)
    Isotyp
    IgG
    Top Product
    Discover our top product RNF128 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RNF128 (Ring Finger Protein 128 (RNF128))
    Andere Bezeichnung
    RNF128 (RNF128 Produkte)
    Hintergrund

    Background: E3 ubiquitin-protein ligase that catalyzes \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with \'Lys-48\' linkages and COR1A with \'Lys-63\' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm, sensitizes ectoderm to respond to neural-inducing signals.

    Aliases: E3 ubiquitin protein ligase RNF128 antibody, E3 ubiquitin-protein ligase RNF128 antibody, FLJ23516 antibody, Gene related to anergy in lymphocytes protein antibody, GRAIL antibody, RING finger protein 128 antibody, RN128_HUMAN antibody, RNF128 antibody

    UniProt
    Q8TEB7
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