RNF139 Antikörper (AA 510-664)
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- Target Alle RNF139 Antikörper anzeigen
- RNF139 (Ring Finger Protein 139 (RNF139))
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Bindungsspezifität
- AA 510-664
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF139 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human E3 ubiquitin-protein ligase RNF139 protein (510-664AA)
- Isotyp
- IgG
- Top Product
- Discover our top product RNF139 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- RNF139 (Ring Finger Protein 139 (RNF139))
- Andere Bezeichnung
- RNF139 (RNF139 Produkte)
- Synonyme
- HRCA1 antikoerper, RCA1 antikoerper, TRC8 antikoerper, 4930555P18Rik antikoerper, zgc:175173 antikoerper, rnf139 antikoerper, ring finger protein 139 antikoerper, ring finger protein 139 S homeolog antikoerper, RNF139 antikoerper, Rnf139 antikoerper, rnf139 antikoerper, rnf139.S antikoerper
- Hintergrund
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Background: E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.
Aliases: RNF139 antibody, TRC8 antibody, E3 ubiquitin-protein ligase RNF139 antibody, EC 2.3.2.27 antibody, RING finger protein 139 antibody, RING-type E3 ubiquitin transferase RNF139 antibody, Translocation in renal carcinoma on chromosome 8 protein antibody
- UniProt
- Q8WU17
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