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RNF34 Antikörper (AA 1-220)

RNF34 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7151192
  • Target Alle RNF34 Antikörper anzeigen
    RNF34 (Ring Finger Protein 34 (RNF34))
    Bindungsspezifität
    • 9
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    AA 1-220
    Reaktivität
    • 27
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    • 2
    • 1
    Kaninchen
    Klonalität
    • 28
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser RNF34 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human E3 ubiquitin-protein ligase RNF34 protein (1-220AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RNF34 (Ring Finger Protein 34 (RNF34))
    Andere Bezeichnung
    RNF34 (RNF34 Produkte)
    Synonyme
    CARP-1 antikoerper, CARP1 antikoerper, RFI antikoerper, RIF antikoerper, RIFF antikoerper, hRFI antikoerper, rnf34 antikoerper, AW061037 antikoerper, AW536122 antikoerper, BC004042 antikoerper, C88279 antikoerper, Momo antikoerper, fi35g06 antikoerper, wu:fi35g06 antikoerper, zgc:114043 antikoerper, zgc:171755 antikoerper, ring finger protein 34 antikoerper, E3 ubiquitin-protein ligase RNF34 antikoerper, ring finger protein 34a antikoerper, ring finger protein 34b antikoerper, Residual feed intake antikoerper, RNF34 antikoerper, rnf34 antikoerper, Rnf34 antikoerper, rnf34a antikoerper, rnf34b antikoerper, RFI antikoerper
    Hintergrund

    Background: E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis (PubMed:15069192). May mediate \\\'Lys-48\\\'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway (Ref.13). Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation (PubMed:17121812). Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN (PubMed:18382127). Mediates PPARGC1A proteasomal degradation probably through ubiquitination thereby indirectly regulating the metabolism of brown fat cells (PubMed:22064484). Possibly involved in innate immunity, through \\\'Lys-48\\\'-linked polyubiquitination of NOD1 and its subsequent proteasomal degradation (PubMed:25012219).

    Aliases: CARP 1 antibody, CARP-1 antibody, CARP1 antibody, Caspase regulator CARP1 antibody, Caspases-8 and -10-associated RING finger protein 1 antibody, E3 ubiquitin-protein ligase RNF34 antibody, FYVE-RING finger protein Momo antibody, hRFI antibody, Human RING finger homologous to inhibitor of apoptosis protein antibody, RFI antibody, RIF antibody, RIFF antibody, RING finger protein 34 antibody, RING finger protein RIFF antibody, RNF34 antibody, RNF34_HUMAN antibody

    UniProt
    Q969K3
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