RNF43 Antikörper (AA 566-697) (HRP)

Produktnummer ABIN7151201

Produktdetails anti-RNF43 Antikörper (HRP)

Target: RNF43 (Ring Finger Protein 43 (RNF43))

Bindungsspezifität: AA 566-697

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF43 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF43 protein (566-697AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RNF43

Target: RNF43 (Ring Finger Protein 43 (RNF43))

Andere Bezeichnung: RNF43 (RNF43 Produkte)

Hintergrund:

Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Aliases: RNF43 antibody, E3 ubiquitin-protein ligase RNF43 antibody, EC 2.3.2.27 antibody, RING finger protein 43 antibody, RING-type E3 ubiquitin transferase RNF43 antibody

UniProt: Q68DV7

Pathways: WNT Signalweg