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TRIM13 Antikörper (AA 40-310)

TRIM13 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7151242
  • Target Alle TRIM13 Antikörper anzeigen
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    Bindungsspezifität
    • 15
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-310
    Reaktivität
    • 31
    • 21
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 43
    • 3
    Kaninchen
    Klonalität
    • 44
    • 2
    Polyklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRIM13 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 18
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human E3 ubiquitin-protein ligase TRIM13 protein (40-310AA)
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    Andere Bezeichnung
    TRIM13 (TRIM13 Produkte)
    Hintergrund

    Background: E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.

    Aliases: B cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, B-cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, CAR antibody, DLEU5 antibody, E3 ubiquitin-protein ligase TRIM13 antibody, HGNC:9976 antibody, LEU5 antibody, Leukemia associated protein 5 antibody, Leukemia-associated protein 5 antibody, Putative tumor suppressor RFP2 antibody, Ret finger protein 2 antibody, RFP2 antibody, RING finger protein 77 antibody, RNF77 antibody, TRI13_HUMAN antibody, Trim13 antibody, Tripartite motif protein 13 antibody, Tripartite motif-containing protein 13 antibody

    UniProt
    O60858
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