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TRIM13 Antikörper (AA 40-310)

TRIM13 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7151243
  • Target Alle TRIM13 Antikörper anzeigen
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    Bindungsspezifität
    • 15
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-310
    Reaktivität
    • 35
    • 21
    • 10
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 47
    • 3
    Kaninchen
    Klonalität
    • 48
    • 2
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRIM13 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 22
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human E3 ubiquitin-protein ligase TRIM13 protein (40-310AA)
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TRIM13 (Tripartite Motif Containing 13 (TRIM13))
    Andere Bezeichnung
    TRIM13 (TRIM13 Produkte)
    Synonyme
    TRIM13 antikoerper, RFP2 antikoerper, CAR antikoerper, DLEU5 antikoerper, LEU5 antikoerper, RNF77 antikoerper, 3110001L12Rik antikoerper, Rfp2 antikoerper, tripartite motif containing 13 antikoerper, ret finger protein 2 antikoerper, tripartite motif-containing 13 antikoerper, TRIM13 antikoerper, LOC100338599 antikoerper, Trim13 antikoerper
    Hintergrund

    Background: E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.

    Aliases: B cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, B-cell chronic lymphocytic leukemia tumor suppressor Leu5 antibody, CAR antibody, DLEU5 antibody, E3 ubiquitin-protein ligase TRIM13 antibody, HGNC:9976 antibody, LEU5 antibody, Leukemia associated protein 5 antibody, Leukemia-associated protein 5 antibody, Putative tumor suppressor RFP2 antibody, Ret finger protein 2 antibody, RFP2 antibody, RING finger protein 77 antibody, RNF77 antibody, TRI13_HUMAN antibody, Trim13 antibody, Tripartite motif protein 13 antibody, Tripartite motif-containing protein 13 antibody

    UniProt
    O60858
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