TRIM33 Antikörper (AA 1-273) (Biotin)

Produktnummer ABIN7151259

Produktdetails anti-TRIM33 Antikörper (Biotin)

Target: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Bindungsspezifität: AA 1-273

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM33 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase TRIM33 protein (1-273AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRIM33

Target: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Andere Bezeichnung: TRIM33 (TRIM33 Produkte)

Synonyme: TRIM33 antikoerper, ptc7 antikoerper, rfg7 antikoerper, tf1g antikoerper, tif1g antikoerper, tifgamma antikoerper, MGC146665 antikoerper, tif1gamma antikoerper, ECTO antikoerper, PTC7 antikoerper, RFG7 antikoerper, TF1G antikoerper, TIF1G antikoerper, TIF1GAMMA antikoerper, TIFGAMMA antikoerper, ecto antikoerper, 8030451N04Rik antikoerper, AI413936 antikoerper, Ecto antikoerper, Tif1g antikoerper, ectodermin antikoerper, mKIAA1113 antikoerper, cb1085 antikoerper, id:ibd2175 antikoerper, mon antikoerper, wu:fc17f10 antikoerper, zgc:136680 antikoerper, tripartite motif containing 33 antikoerper, tripartite motif containing 33 L homeolog antikoerper, tripartite motif-containing 33 antikoerper, TRIM33 antikoerper, trim33 antikoerper, trim33.L antikoerper, Trim33 antikoerper

Hintergrund:

Background: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).

Aliases: 8030451N04Rik antibody, AI413936 antibody, cb1085 antibody, DKFZp586K1123 antibody, E3 ubiquitin-protein ligase TRIM33 antibody, EC 6.3.2.- antibody, Ectodermin antibody, Ectodermin homolog antibody, FLJ11429 antibody, FLJ32925 antibody, id:ibd2175 antibody, MGC136680 antibody, mKIAA1113 antibody, OTTHUMP00000013662 antibody, OTTHUMP00000013663 antibody, Protein Rfg7 antibody, PTC7 antibody, Ret fused gene 7 antibody, RET-fused gene 7 protein antibody, RFG7 antibody, Rfg7 protein antibody, TF1G antibody, TIF1 gamma antibody, TIF1-gamma antibody, TIF1G antibody, TIF1GAMMA antibody, TIFGAMMA antibody, Transcription intermediary factor 1-gamma antibody, Transcriptional intermediary factor 1 gamma antibody, TRI33_HUMAN antibody, trim33 antibody, Tripartite motif containing 33 antibody, Tripartite motif containing 33 protein antibody, tripartite motif-containing 33 antibody, Tripartite motif-containing protein 33 antibody, wu:fc17f10 antibody, zgc:136680 antibody

UniProt: Q9UPN9