TRIM37 Antikörper (AA 301-600) (Biotin)

Produktnummer ABIN7151267

Produktdetails anti-TRIM37 Antikörper (Biotin)

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Bindungsspezifität: AA 301-600

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM37 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase TRIM37 protein (301-600AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Andere Bezeichnung: TRIM37 (TRIM37 Produkte)

Hintergrund:

Background: E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of \'Lys-119\' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).

Aliases: E3 ubiquitin protein ligase TRIM37 antibody, E3 ubiquitin-protein ligase TRIM37 antibody, KIAA0898 antibody, MUL antibody, MUL protein antibody, Mulibrey nanism gene antibody, Mulibrey nanism protein antibody, POB 1 antibody, POB1 antibody, RING B box coiled coil protein antibody, TEF 3 antibody, TEF3 antibody, TRI37_HUMAN antibody, TRIM 37 antibody, Trim37 antibody, Tripartite motif containing 37 antibody, Tripartite motif containing 37 protein antibody, Tripartite motif containing protein 37 antibody, Tripartite motif-containing protein 37 antibody

UniProt: O94972