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EHD3 Antikörper (AA 269-498) (Biotin)

EHD3 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7151462
  • Target Alle EHD3 Antikörper anzeigen
    EHD3 (EH-Domain Containing 3 (EHD3))
    Bindungsspezifität
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 269-498
    Reaktivität
    • 25
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 22
    • 3
    Kaninchen
    Klonalität
    • 23
    • 2
    Polyklonal
    Konjugat
    • 14
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EHD3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 15
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human EH domain-containing protein 3 protein (269-498AA)
    Isotyp
    IgG
    Top Product
    Discover our top product EHD3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EHD3 (EH-Domain Containing 3 (EHD3))
    Andere Bezeichnung
    EHD3 (EHD3 Produkte)
    Synonyme
    PAST3 antikoerper, Ehd2 antikoerper, EHD3 antikoerper, si:ch211-147c1.2 antikoerper, MGC146452 antikoerper, EH domain containing 3 antikoerper, EH-domain containing 3 antikoerper, EH domain containing 3 L homeolog antikoerper, EHD3 antikoerper, Ehd3 antikoerper, ehd3 antikoerper, ehd3.L antikoerper
    Hintergrund

    Background: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250). In vitro causes tubulation of endocytic membranes (PubMed:24019528). Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology (PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025). Involved in the recycling of internalized D1 dopamine receptor (PubMed:21791287). Plays a role in cardiac protein trafficking probably implicating ANK2 (PubMed:20489164). Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte exitability and cardiac conduction (By similarity). In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function (By similarity). Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance (PubMed:23781025). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis, possibly sharing redundant functions with EHD1 (PubMed:25686250).

    Aliases: EHD3 antibody, EHD2 antibody, PAST3EH domain-containing protein 3 antibody, PAST homolog 3 antibody

    UniProt
    Q9NZN3
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