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ERAP1 Antikörper (AA 642-941) (Biotin)

ERAP1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7151656
  • Target Alle ERAP1 Antikörper anzeigen
    ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
    Bindungsspezifität
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 642-941
    Reaktivität
    • 32
    • 17
    • 15
    • 1
    • 1
    Human
    Wirt
    • 30
    • 2
    Kaninchen
    Klonalität
    • 28
    • 4
    Polyklonal
    Konjugat
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ERAP1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 19
    • 14
    • 10
    • 10
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Endoplasmic reticulum aminopeptidase 1 protein (642-941AA)
    Isotyp
    IgG
    Top Product
    Discover our top product ERAP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
    Andere Bezeichnung
    ERAP1 (ERAP1 Produkte)
    Synonyme
    MGC166160 antikoerper, DKFZp469C044 antikoerper, ARTS-1 antikoerper, A-LAP antikoerper, ALAP antikoerper, APPILS antikoerper, ARTS1 antikoerper, ERAAP antikoerper, ERAAP1 antikoerper, PILS-AP antikoerper, PILSAP antikoerper, Arts1 antikoerper, PILSA antikoerper, Appils antikoerper, endoplasmic reticulum aminopeptidase 1 antikoerper, endoplasmic reticulum aminopeptidase 1b antikoerper, ERAP1 antikoerper, erap1 antikoerper, erap1b antikoerper, Erap1 antikoerper
    Hintergrund

    Background: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

    Aliases: A LAP antibody, A-LAP antibody, Adipocyte derived leucine aminopeptidase antibody, Adipocyte-derived leucine aminopeptidase antibody, ALAP antibody, Aminopeptidase PILS antibody, Aminopeptidase regulator of TNFR1 shedding antibody, APPILS antibody, ARTS 1 antibody, ARTS-1 antibody, Arts1 antibody, Endoplasmic reticulum aminopeptidase 1 antibody, Endoplasmic reticulum aminopeptidase associated with antigen processing antibody, ERAAP antibody, ERAAP1 antibody, ERAP 1 antibody, Erap1 antibody, ERAP1_HUMAN antibody, KIAA0525 antibody, kiaa0525 protein antibody, PILS AP antibody, PILS-AP antibody, PILSA antibody, PILSAP antibody, Puromycin insensitive leucyl specific aminopeptidase antibody, Puromycin-insensitive leucyl-specific aminopeptidase antibody, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody, type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody, VEGF-induced aminopeptidase antibody

    UniProt
    Q9NZ08
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