NGEF Antikörper (AA 495-710) (FITC)
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- Target Alle NGEF Antikörper anzeigen
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
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Bindungsspezifität
- AA 495-710
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NGEF Antikörper ist konjugiert mit FITC
- Applikation
- Bitte anfragen
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Ephexin-1 protein (495-710AA)
- Isotyp
- IgG
- Top Product
- Discover our top product NGEF Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
- Andere Bezeichnung
- NGEF (NGEF Produkte)
- Synonyme
- Ephexin-1 antikoerper, ARHGEF27 antikoerper, EPHEXIN antikoerper, Tims2 antikoerper, ephexin antikoerper, Besh3 antikoerper, ephexin-1 antikoerper, neuronal guanine nucleotide exchange factor antikoerper, NGEF antikoerper, Ngef antikoerper
- Hintergrund
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Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
Aliases: ARHGEF27 antibody, Eph receptor-interacting exchange protein antibody, Eph-interacting exchange protein antibody, EPHEXIN antibody, Ephexin-1 antibody, Guanine nucleotide exchange factor, neuronal antibody, Neuronal guanine nucleotide exchange factor antibody, Ngef antibody, NGEF_HUMAN antibody
- UniProt
- Q8N5V2
- Pathways
- Neurotrophin Signalübertragung
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