EPHA1 Antikörper (AA 296-414)
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- Target Alle EPHA1 Antikörper anzeigen
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
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Bindungsspezifität
- AA 296-414
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPHA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Ephrin type-A receptor 1 protein (296-414AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- EPHA1 (Ephrin Type A Receptor 1 (EPHA1))
- Andere Bezeichnung
- EPHA1 (EPHA1 Produkte)
- Synonyme
- EPH antikoerper, EPHT antikoerper, EPHT1 antikoerper, 5730453L17Rik antikoerper, AL033318 antikoerper, Eph antikoerper, Esk antikoerper, EPHA9 antikoerper, EPH receptor A1 antikoerper, Eph receptor A1 antikoerper, EPHA1 antikoerper, Epha1 antikoerper
- Hintergrund
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Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
Aliases: EPH antibody, EPH receptor A1 antibody, EPH tyrosine kinase 1 antibody, EPH tyrosine kinase antibody, Epha1 antibody, EPHA1_HUMAN antibody, Ephrin receptor Eph A1 antibody, Ephrin type A receptor 1 antibody, Ephrin type-A receptor 1 antibody, EPHT 1 antibody, EPHT antibody, EPHT1 antibody, Erythropoietin producing hepatoma amplified sequence antibody, Erythropoietin-producing hepatoma receptor antibody, Esk antibody, hEpha1 antibody, MGC163163 antibody, Oncogene EPH antibody, Soluble EPHA1 variant 1 antibody, Soluble EPHA1 variant 2 antibody, Tyrosine protein kinase receptor EPH antibody, Tyrosine-protein kinase receptor EPH antibody
- UniProt
- P21709
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