EPH Receptor B4 Antikörper (AA 300-540)
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- Target Alle EPH Receptor B4 (EPHB4) Antikörper anzeigen
- EPH Receptor B4 (EPHB4)
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Bindungsspezifität
- AA 300-540
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPH Receptor B4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Ephrin type-B receptor 4 protein (300-540AA)
- Isotyp
- IgG
- Top Product
- Discover our top product EPHB4 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- EPH Receptor B4 (EPHB4)
- Andere Bezeichnung
- EPHB4 (EPHB4 Produkte)
- Hintergrund
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Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
Aliases: Ephb4 antibody, EPHB4_HUMAN antibody, Ephrin receptor EphB4 antibody, Ephrin type-B receptor 4 antibody, Hepatoma Transmembrane Kinase antibody, HTK antibody, MYK 1 antibody, MYK1 antibody, TYRO 11 antibody, TYRO11 antibody, Tyrosine-protein kinase receptor HTK antibody, Tyrosine-protein kinase TYRO11 antibody
- UniProt
- P54760
- Pathways
- RTK Signalweg
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