Ephrin B2 Antikörper (AA 28-229)

Produktnummer ABIN7151879

Produktdetails anti-Ephrin B2 Antikörper

Target: Ephrin B2 (EFNB2)

Bindungsspezifität: AA 28-229

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Ephrin-B2 protein (28-229AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Ephrin B2

Target: Ephrin B2 (EFNB2)

Andere Bezeichnung: EFNB2 (EFNB2 Produkte)

Synonyme: EFNB2 antikoerper, efnb2 antikoerper, ephrin-B2 antikoerper, htkl antikoerper, eplg5 antikoerper, htk-l antikoerper, lerk5 antikoerper, ephrinB2 antikoerper, efnb2a antikoerper, MGC68890 antikoerper, efnb2b antikoerper, ELF-2 antikoerper, Epl5 antikoerper, Eplg5 antikoerper, Htk-L antikoerper, LERK-5 antikoerper, Lerk5 antikoerper, NLERK-1 antikoerper, EPLG5 antikoerper, HTKL antikoerper, LERK5 antikoerper, ephrin B2 antikoerper, ephrin-B2 precursor antikoerper, ephrin B2 L homeolog antikoerper, ephrin B2 S homeolog antikoerper, EFNB2 antikoerper, efnb2 antikoerper, efnb2.L antikoerper, efnb2.S antikoerper, Efnb2 antikoerper

Hintergrund:

Background: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

Aliases: EFN B2 antibody, EFNB 2 antibody, Efnb2 antibody, EFNB2_HUMAN antibody, Eph related receptor tyrosine kinase ligand 5 antibody, EPH-related receptor tyrosine kinase ligand 5 antibody, ephrin B2 antibody, Ephrin-B2 antibody, EphrinB2 antibody, EPLG 5 antibody, EPLG5 antibody, Htk L antibody, HTK ligand antibody, HTK-L antibody, HTKL antibody, LERK 5 antibody, LERK-5 antibody, LERK5 antibody, Ligand of eph related kinase 5 antibody, MGC126226 antibody, MGC126227 antibody, MGC126228 antibody, OTTMUSP00000024973 antibody

UniProt: P52799

Pathways: RTK Signalweg, Regulation of Muscle Cell Differentiation