EDEM2 Antikörper (AA 22-300) (Biotin)

Produktnummer ABIN7151975

Produktdetails anti-EDEM2 Antikörper (Biotin)

Target: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Bindungsspezifität: AA 22-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDEM2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 2 protein (22-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EDEM2

Target: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Andere Bezeichnung: EDEM2 (EDEM2 Produkte)

Synonyme: C20orf31 antikoerper, C20orf49 antikoerper, bA4204.1 antikoerper, 9530090G24Rik antikoerper, AI327354 antikoerper, RGD1303074 antikoerper, MGC88910 antikoerper, DKFZp459A0314 antikoerper, ER degradation enhancing alpha-mannosidase like protein 2 antikoerper, ER degradation enhancer, mannosidase alpha-like 2 antikoerper, EDEM2 antikoerper, Edem2 antikoerper, edem2 antikoerper

Hintergrund:

Background: Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.

Aliases: bA4204.1 antibody, C20orf31 antibody, C20orf49 antibody, EDEM 2 antibody, EDEM2 antibody, EDEM2_HUMAN antibody, ER degradation enhancer mannosidase alpha like 2 antibody, ER degradation enhancing alpha mannosidase like 2 antibody, ER degradation enhancing alpha mannosidase like protein 2 antibody, ER degradation enhancing mannosidase like protein 2 antibody, ER degradation-enhancing alpha-mannosidase-like 2 antibody, FLJ10783 antibody, UNQ573/PRO1135 antibody

UniProt: Q9BV94