ERLIN2 Antikörper (AA 212-339)

Produktnummer ABIN7151997

Produktdetails anti-ERLIN2 Antikörper

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Bindungsspezifität: AA 212-339

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERLIN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Erlin-2 protein (212-339AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERLIN2

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Andere Bezeichnung: ERLIN2 (ERLIN2 Produkte)

Synonyme: C8orf2 antikoerper, Erlin-2 antikoerper, NET32 antikoerper, SPFH2 antikoerper, SPG18 antikoerper, BC036333 antikoerper, C87251 antikoerper, Spfh2 antikoerper, Erlin-2-B antikoerper, erlin1 antikoerper, spfh1 antikoerper, spfh2 antikoerper, spfh2-B antikoerper, RGD1309010 antikoerper, SPFH domain-containing protein 2-A antikoerper, erlin2 antikoerper, erlin2-a antikoerper, erlin2-b antikoerper, spfh2-A antikoerper, ER lipid raft associated 2 antikoerper, erlin-2 antikoerper, Erlin-2 antikoerper, ER lipid raft associated 2 S homeolog antikoerper, ER lipid raft associated 2 L homeolog antikoerper, ERLIN2 antikoerper, erlin2 antikoerper, Tsp_03442 antikoerper, erln2 antikoerper, Erlin2 antikoerper, erlin2.S antikoerper, erlin2.L antikoerper

Hintergrund:

Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).

Aliases: C8orf2 antibody, Chromosome 8 open reading frame 2 antibody, Endoplasmic reticulum lipid raft associated protein 2 antibody, Endoplasmic reticulum lipid raft-associated protein 2 antibody, ER lipid raft associated 2 antibody, ERLIN 2 antibody, Erlin-2 antibody, ERLIN2 antibody, ERLN2_HUMAN antibody, HGNC:1356 antibody, MGC87072 antibody, NET32 antibody, SPFH 2 antibody, SPFH domain containing protein 2 antibody, SPFH domain family member 2 antibody, SPFH domain-containing protein 2 antibody, SPFH2 antibody, SPG18 antibody, Stomatin prohibitin flotillin HflC/K domain containing protein 2 antibody, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 antibody

UniProt: O94905