ERO1LB Antikörper (AA 101-400)

Produktnummer ABIN7152004

Produktdetails anti-ERO1LB Antikörper

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Bindungsspezifität: AA 101-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERO1LB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ERO1-like protein beta protein (101-400AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERO1LB

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Andere Bezeichnung: ERO1B (ERO1LB Produkte)

Synonyme: RGD1563548 antikoerper, 1300013B24Rik antikoerper, 1700065B09Rik antikoerper, AI447560 antikoerper, ero1-beta antikoerper, endoplasmic reticulum oxidoreductase 1 beta antikoerper, ERO1-like beta (S. cerevisiae) antikoerper, Ero1b antikoerper, ERO1B antikoerper, Ero1lb antikoerper

Hintergrund:

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Aliases: Endoplasmic oxidoreductin-1-like protein B antibody, Endoplasmic reticulum oxidoreductin-1-like protein B antibody, ERO1, S. cerevisiae, homolog of, beta antibody, ERO1-L-beta antibody, ERO1-like beta (S. cerevisiae) antibody, ERO1-like protein beta antibody, ERO1B_HUMAN antibody, Ero1lb antibody, Oxidoreductin-1-L-beta antibody

UniProt: Q86YB8

Pathways: SARS-CoV-2 Protein Interaktom