EIF3I Antikörper (AA 1-323) (Biotin)
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- Target Alle EIF3I Antikörper anzeigen
- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
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Bindungsspezifität
- AA 1-323
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EIF3I Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Eukaryotic translation initiation factor 3 subunit I protein (1-323AA)
- Isotyp
- IgG
- Top Product
- Discover our top product EIF3I Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- EIF3I (Eukaryotic Translation Initiation Factor 3, Subunit I (EIF3I))
- Andere Bezeichnung
- EIF3I (EIF3I Produkte)
- Synonyme
- EIF3S2 antikoerper, PRO2242 antikoerper, TRIP-1 antikoerper, TRIP1 antikoerper, eIF3-beta antikoerper, eIF3-p36 antikoerper, 36kDa antikoerper, D4Ertd632e antikoerper, Eif3s2 antikoerper, Trip1 antikoerper, eIF-3-beta antikoerper, eIF3 p36 antikoerper, eif3s2 antikoerper, hm:zehn0464 antikoerper, wu:fb62b08 antikoerper, zgc:56211 antikoerper, zgc:77823 antikoerper, CaO19.2967 antikoerper, eIF-3 39 kDa subunit homolog antikoerper, eIF3i antikoerper, eif3-beta antikoerper, eif3-p36 antikoerper, eif3i antikoerper, pro2242 antikoerper, trip-1 antikoerper, trip1 antikoerper, eukaryotic translation initiation factor 3 subunit I antikoerper, eukaryotic translation initiation factor 3, subunit I antikoerper, Eukaryotic Initiation Factor antikoerper, Eukaryotic translation initiation factor 3 subunit I antikoerper, translation initiation factor eIF3 subunit i antikoerper, eukaryotic translation initiation factor 3 subunit I L homeolog antikoerper, EIF3I antikoerper, Eif3i antikoerper, eif-3.I antikoerper, eIF3i antikoerper, eif3i antikoerper, TIF34 antikoerper, eif3i.L antikoerper
- Hintergrund
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Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Aliases: eIF-3-beta antibody, eIF3 beta antibody, eIF3 p36 antibody, eIF3-beta antibody, eIF3-p36 antibody, eIF3i antibody, EIF3I_HUMAN antibody, EIF3S2 antibody, EIF3S2, formerly antibody, Eukaryotic translation initiation factor 3 subunit 2 antibody, Eukaryotic translation initiation factor 3 subunit 2 beta antibody, Eukaryotic translation initiation factor 3 subunit I antibody, eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD antibody, eukaryotic translation initiation factor 3, subunit 2 beta, 36 kDa antibody, eukaryotic translation initiation factor 3, subunit 2, formerly antibody, eukaryotic translation initiation factor 3, subunit I antibody, Predicted protein of HQ2242 antibody, PRO2242 antibody, TGF beta receptor interacting protein 1 antibody, TGF-beta receptor-interacting protein 1 antibody, TGFbeta receptor interacting protein 1 antibody, TGFbeta receptor-interacting protein 1 antibody, TRIP 1 antibody, TRIP-1 antibody, TRIP1 antibody
- UniProt
- Q13347
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Ribonucleoprotein Complex Subunit Organization, Synthesis of DNA
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