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DIS3 Antikörper (AA 30-187)

DIS3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7152297
  • Target Alle DIS3 Antikörper anzeigen
    DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-187
    Reaktivität
    • 44
    • 16
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 39
    • 5
    Kaninchen
    Klonalität
    • 42
    • 2
    Polyklonal
    Konjugat
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DIS3 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 21
    • 14
    • 7
    • 6
    • 4
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Exosome complex exonuclease RRP44 protein (30-187AA)
    Isotyp
    IgG
    Top Product
    Discover our top product DIS3 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
    Andere Bezeichnung
    DIS3 (DIS3 Produkte)
    Synonyme
    EXOSC11 antikoerper, KIAA1008 antikoerper, RP11-342J4.3 antikoerper, RRP44 antikoerper, bA555G22.1 antikoerper, dis3p antikoerper, DIS3 antikoerper, 2810028N01Rik antikoerper, RGD1304646 antikoerper, wu:fb08g12 antikoerper, dis3 antikoerper, DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 antikoerper, Dis3 antikoerper, dis3 antikoerper, dis3.L antikoerper
    Hintergrund

    Background: Putative catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. DIS3 has both 3\'-5\' exonuclease and endonuclease activities.

    Aliases: 2810028N01Rik antibody, bA555G22 antibody, Dis3 antibody, DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease antibody, DIS3 mitotic control homolog (S. cerevisiae) antibody, DIS3 mitotic control homolog antibody, DIS3 mitotic control, S. cerevisiae, homolog of antibody, dis3p antibody, EXOSC11 antibody, Exosome complex exonuclease RRP44 antibody, exosome component 11 antibody, KIAA1008 antibody, Mitotic control protein dis3 homolog antibody, Protein DIS3 homolog antibody, Ribosomal RNA processing protein 44 antibody, Ribosomal RNA processing protein 44, S. cerevisiae, homolog of antibody, Ribosomal RNA-processing protein 44 antibody, RP11-342J4.3 antibody, RRP44 antibody, RRP44_HUMAN antibody

    UniProt
    Q9Y2L1
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