Exportin 2 Antikörper (AA 713-971) (Biotin)

Produktnummer ABIN7152322

Produktdetails anti-Exportin 2 Antikörper (Biotin)

Target: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Bindungsspezifität: AA 713-971

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Exportin 2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Exportin-2 protein (713-971AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Exportin 2

Target: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Andere Bezeichnung: CSE1L (CSE1L Produkte)

Synonyme: BcDNA:LD14270 antikoerper, CAS antikoerper, CG13281 antikoerper, Dcas antikoerper, Dmel\\CG13281 antikoerper, cas antikoerper, dcas antikoerper, l(2)k03902 antikoerper, CSE1L antikoerper, XPO2 antikoerper, Exportin-2 antikoerper, DKFZp459E1929 antikoerper, 2610100P18Rik antikoerper, AA407533 antikoerper, Capts antikoerper, Cas antikoerper, Xpo2 antikoerper, xpo2 antikoerper, CSE1 antikoerper, CAS/CSE1 segregation protein antikoerper, chromosome segregation 1 like antikoerper, exportin-2 antikoerper, chromosome segregation 1-like (S. cerevisiae) antikoerper, CSE1 chromosome segregation 1-like (yeast) antikoerper, CSE1 chromosome segregation 1-like L homeolog antikoerper, Cas antikoerper, CSE1L antikoerper, LOC100542094 antikoerper, cse1l antikoerper, Cse1l antikoerper, cse1l.L antikoerper

Hintergrund:

Background: Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

Aliases: CAS antibody, Cellular apoptosis susceptibility protein antibody, Chromosome segregation 1 (yeast homolog) like antibody, Chromosome segregation 1 Like antibody, Chromosome segregation 1 like protein antibody, Chromosome segregation 1-like protein antibody, Chromosome segregation gene CSE1 antibody, CSE 1 antibody, CSE 1 chromosome segregation 1 like antibody, CSE 1 chromosome segregation 1 like protein antibody, CSE 1L antibody, CSE1 antibody, CSE1 chromosome segregation 1 like (yeast) antibody, CSE1 chromosome segregation 1 like antibody, CSE1 chromosome segregation 1 like protein antibody, CSE1L antibody, Exp 2 antibody, Exp2 antibody, Exportin 2 antibody, Exportin-2 antibody, Exportin2 antibody, Importin alpha re exporter antibody, Importin-alpha re-exporter antibody, MGC117283 antibody, MGC130036 antibody, MGC130037 antibody, XPO 2 antibody, XPO2 antibody, XPO2_HUMAN antibody

UniProt: P55060

Pathways: Protein targeting to Nucleus