SERF2 Antikörper (AA 107-224)

Produktnummer ABIN7152338

Produktdetails anti-SERF2 Antikörper

Target: SERF2 (Small EDRK-Rich Factor 2 (SERF2))

Bindungsspezifität: AA 107-224

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERF2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Extracellular serine/threonine protein kinase FAM20C protein (107-224AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SERF2

Target: SERF2 (Small EDRK-Rich Factor 2 (SERF2))

Andere Bezeichnung: FAM2C (SERF2 Produkte)

Synonyme: 4F5REL antikoerper, FAM2C antikoerper, H4F5REL antikoerper, HsT17089 antikoerper, C80083 antikoerper, Msmac1l antikoerper, m4F5rel antikoerper, small EDRK-rich factor 2 antikoerper, SERF2 antikoerper, Serf2 antikoerper

Hintergrund:

Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).

Aliases: C76981 antibody, Dentin matrix protein 4 antibody, DKFZp547C074 antibody, DMP-4 antibody, DMP4 antibody, DMP4_HUMAN antibody, Extracellular serine/threonine protein kinase Fam20C antibody, Fam20c antibody, Family with sequence similarity 20 member C antibody, GEF CK antibody, Golgi enriched fraction casein kinase antibody, Protein FAM20C antibody, RNS antibody

UniProt: Q8IXL6