EYA4 Antikörper (AA 153-224)

Produktnummer ABIN7152365

Produktdetails anti-EYA4 Antikörper

Target: EYA4 (Eyes Absent Homolog 4 (EYA4))

Bindungsspezifität: AA 153-224

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EYA4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Eyes absent homolog 4 protein (153-224AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EYA4

Target: EYA4 (Eyes Absent Homolog 4 (EYA4))

Andere Bezeichnung: EYA4 (EYA4 Produkte)

Synonyme: B130023L16Rik antikoerper, CMD1J antikoerper, DFNA10 antikoerper, EYA transcriptional coactivator and phosphatase 4 antikoerper, Eya4 antikoerper, EYA4 antikoerper

Hintergrund:

Background: Tyrosine phosphatase that specifically dephosphorylates \\\'Tyr-142\\\' of histone H2AX (H2AXY142ph). \\\'Tyr-142\\\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).

Aliases: CMD1J antibody, Deafness, autosomal dominant 10 antibody, DFNA 10 antibody, DFNA10 antibody, dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody, dJ78N10.1 (eyes absent) antibody, EYA 4 antibody, eya4 antibody, EYA4_HUMAN antibody, Eyes absent 4 antibody, Eyes absent homolog 4 (Drosophila) antibody, Eyes absent homolog 4 antibody, HGNC:3522 antibody, OTTHUMP00000040267 antibody

UniProt: O95677

Pathways: Sensory Perception of Sound