FBXL5 Antikörper (AA 1-310)

Produktnummer ABIN7152484

Produktdetails anti-FBXL5 Antikörper

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Bindungsspezifität: AA 1-310

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human F-box/LRR-repeat protein 5 protein (1-310AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FBXL5

Target: FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))

Andere Bezeichnung: FBXL5 (FBXL5 Produkte)

Hintergrund:

Background: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

Aliases: F box and leucine rich repeat protein 5 antibody, F box protein FBL5 antibody, F box/LRR repeat protein 5 antibody, F-box and leucine-rich repeat protein 5 antibody, F-box protein FBL4/FBL5 antibody, F-box/LRR-repeat protein 5 antibody, FBL4 antibody, FBL5 antibody, FBXL5 antibody, FBXL5_HUMAN antibody, FLR1 antibody, p45SKP2 like protein antibody, p45SKP2-like protein antibody

UniProt: Q9UKA1

Pathways: Transition Metal Ion Homeostasis