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FBXW11 Antikörper (AA 1-140)

FBXW11 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7152490
  • Target Alle FBXW11 Antikörper anzeigen
    FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-140
    Reaktivität
    • 26
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 24
    • 2
    Kaninchen
    Klonalität
    • 24
    • 2
    Polyklonal
    Konjugat
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser FBXW11 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 17
    • 15
    • 13
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human F-box/WD repeat-containing protein 11 protein (1-140AA)
    Isotyp
    IgG
    Top Product
    Discover our top product FBXW11 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
    Andere Bezeichnung
    FBXW11 (FBXW11 Produkte)
    Synonyme
    BTRC2 antikoerper, BTRCP2 antikoerper, FBW1B antikoerper, FBXW1B antikoerper, Fbw11 antikoerper, Hos antikoerper, 2310065A07Rik antikoerper, AA536858 antikoerper, Fbxw1b antikoerper, HOS antikoerper, btrc2 antikoerper, fbxw11a antikoerper, wu:fa12e12 antikoerper, wu:fb11f03 antikoerper, zgc:63728 antikoerper, fbxw11 antikoerper, fbxw11b antikoerper, fbxw1b antikoerper, wu:fd14d12 antikoerper, wu:fi43f07 antikoerper, F-box and WD repeat domain containing 11 antikoerper, F-box and WD-40 domain protein 11 antikoerper, F-box/WD repeat-containing protein 11 antikoerper, F-box and WD repeat domain containing 11b antikoerper, F-box and WD repeat domain containing 11a antikoerper, FBXW11 antikoerper, Fbxw11 antikoerper, LOC100199403 antikoerper, fbxw11b antikoerper, fbxw11a antikoerper
    Hintergrund

    Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressing through S phase and thus may function in the intra-S-phase checkpoint. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and phosphorylated PER2. Is target of human immunodeficiency virus type 1 (HIV-1) protein VPU to polyubiquitinate and deplete BST2 from cells and antagonize its antiviral action.

    Aliases: beta Transducin Repeat Containing Protein 2 antibody, BTRC2 antibody, BTRCP2 antibody, F-box and WD repeats protein beta-TrCP2 antibody, F-box and WD-40 Domain Protein 1B antibody, F-box Protein FBW1B antibody, F-box/WD repeat-containing protein 11 antibody, F-box/WD repeat-containing protein 1B antibody, FBW1B antibody, FBW1B_HUMAN antibody, FBXW11 antibody, FBXW1B antibody, Homologous to Slimb protein antibody, HOS antibody

    UniProt
    Q9UKB1
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