SSRP1 Antikörper (AA 1-242)

Produktnummer ABIN7152517

Produktdetails anti-SSRP1 Antikörper

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Bindungsspezifität: AA 1-242

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human FACT complex subunit SSRP1 protein (1-242AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:2000-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SSRP1

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Andere Bezeichnung: SSRP1 (SSRP1 Produkte)

Synonyme: ATHMG antikoerper, NFD antikoerper, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D antikoerper, SSRP1 antikoerper, high mobility group antikoerper, ssrp1 antikoerper, CG4817 antikoerper, Cf5 antikoerper, Dmel\\CG4817 antikoerper, DssRP antikoerper, SSRP antikoerper, dSSRP antikoerper, dSSRP1 antikoerper, dSsrp antikoerper, ssrp antikoerper, Ssrp1 antikoerper, DDBDRAFT_0188842 antikoerper, DDBDRAFT_0216434 antikoerper, DDB_0188842 antikoerper, DDB_0216434 antikoerper, wu:fa11b03 antikoerper, wu:fd10f06 antikoerper, FACT antikoerper, FACT80 antikoerper, T160 antikoerper, CIIDBP antikoerper, C81323 antikoerper, Hmg1-rs1 antikoerper, Hmgi-rs3 antikoerper, Hmgox antikoerper, high mobility group antikoerper, FACT complex subunit Ssrp1 antikoerper, FACT complex subunit SSRP1 antikoerper, Structure specific recognition protein antikoerper, structure specific recognition protein 1 antikoerper, transcription factor protein antikoerper, structure specific recognition protein 1a antikoerper, SSRP1 protein antikoerper, structure specific recognition protein 1 S homeolog antikoerper, HMG antikoerper, CpipJ_CPIJ002953 antikoerper, CpipJ_CPIJ020011 antikoerper, CMU_019430 antikoerper, Tsp_07406 antikoerper, LOC100286423 antikoerper, Ssrp antikoerper, ssrp1 antikoerper, SSRP1 antikoerper, ssrp1a antikoerper, nfd110 antikoerper, ssrp1.S antikoerper, Ssrp1 antikoerper

Hintergrund:

Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of \'Ser-392\' of p53/TP53 via its association with CK2 (casein kinase II). Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin. May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA. Also acts as a transcriptional coactivator for p63/TP63.

Aliases: Chromatin-specific transcription elongation factor 80 kDa subunit antibody, Cisplatin DNA SSRP antibody, Facilitates chromatin remodeling 80 kDa subunit antibody, Facilitates chromatin transcription complex 80 kDa subunit antibody, Facilitates chromatin transcription complex subunit SSRP1 antibody, FACT 80 kDa subunit antibody, FACT complex subunit SSRP1 antibody, FACT80 antibody, FACTp80 antibody, hSSRP1 antibody, Recombination signal sequence recognition protein 1 antibody, Recombination signal sequence recognition protein antibody, SSRP 1 antibody, SSRP1 antibody, SSRP1_HUMAN antibody, Structure specific recognition protein 1 antibody, Structure-specific recognition protein 1 antibody, T160 antibody

UniProt: Q08945

Pathways: Chromatin Binding