GFER Antikörper (AA 81-205)

Produktnummer ABIN7152531

Der Kaninchen Polyklonal Anti-GFER-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, GFER in Proben von Human zu detektieren.

Kurzübersicht für GFER Antikörper (AA 81-205) (ABIN7152531)

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFER Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-GFER Antikörper

Bindungsspezifität: AA 81-205

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human FAD-linked sulfhydryl oxidase ALR protein (81-205AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GFER

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Andere Bezeichnung: GFER

Hintergrund:

Background: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.

Aliases: ALR_HUMAN antibody, Augmenter of liver regeneration antibody, ERV1 antibody, ERV1 homolog antibody, Erv1 like growth factor antibody, FAD-linked sulfhydryl oxidase ALR antibody, GFER antibody, Growth factor augmenter of liver regeneration antibody, Growth factor erv1 like antibody, Hepatic regenerative stimulation substance antibody, Hepatopoietin antibody, Hepatopoietin protein antibody, hERV1 antibody, HPO antibody, HPO1 antibody, HPO2 antibody, HSS antibody

UniProt: P55789

Pathways: SARS-CoV-2 Protein Interaktom