FANCI Antikörper (AA 180-252) (Biotin)

Produktnummer ABIN7152558

Produktdetails anti-FANCI Antikörper (Biotin)

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Bindungsspezifität: AA 180-252

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCI Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Fanconi anemia group I protein (180-252AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FANCI

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Andere Bezeichnung: FANCI (FANCI Produkte)

Synonyme: KIAA1794 antikoerper, Fanconi anemia complementation group I antikoerper, Fanconi anemia, complementation group I antikoerper, FANCI antikoerper, Fanci antikoerper

Hintergrund:

Background: Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.

Aliases: FANCI antibody, FANCI gene antibody, FANCI_HUMAN antibody, Fanconi anemia group I protein antibody, Fanconi anemia, complementation group I antibody, FLJ10719 antibody, FLJ14658 antibody, KIAA1794 antibody, Protein FACI antibody, Protein FANCI antibody

UniProt: Q9NVI1

Pathways: DNA Reparatur