FCRL3 Antikörper (AA 122-222)
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- Target Alle FCRL3 Antikörper anzeigen
- FCRL3 (Fc Receptor-Like 3 (FCRL3))
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Bindungsspezifität
- AA 122-222
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FCRL3 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Fc receptor-like protein 3 protein (122-222AA)
- Isotyp
- IgG
- Top Product
- Discover our top product FCRL3 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FCRL3 (Fc Receptor-Like 3 (FCRL3))
- Andere Bezeichnung
- FCRL3 (FCRL3 Produkte)
- Synonyme
- CD307c antikoerper, FCRH3 antikoerper, IFGP3 antikoerper, IRTA3 antikoerper, SPAP2 antikoerper, fcrh3 antikoerper, ifgp3 antikoerper, irta3 antikoerper, spap2 antikoerper, xfl1.2 antikoerper, Fc receptor like 3 antikoerper, Fc receptor-like 3 L homeolog antikoerper, Fc receptor-like 3 antikoerper, Fc receptor-like 3 S homeolog antikoerper, FCRL3 antikoerper, fcrl3.L antikoerper, fcrl3 antikoerper, fcrl3.S antikoerper
- Hintergrund
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Background: Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).
Aliases: CD307c antibody, Fc receptor homolog 3 antibody, Fc receptor-like protein 3 antibody, FcR-like protein 3 antibody, FcRH3 antibody, FcRL3 antibody, FCRL3_HUMAN antibody, hIFGP3 antibody, IFGP family protein 3 antibody, IFGP3 antibody, Immune receptor translocation-associated protein 3 antibody, Immunoglobulin superfamily receptor translocation associated protein 3 antibody, IRTA3 antibody, SH2 domain-containing phosphatase anchor protein 2 antibody, SPAP2 antibody
- UniProt
- Q96P31
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