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FCRL3 Antikörper (AA 122-222)

FCRL3 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7152658
  • Target Alle FCRL3 Antikörper anzeigen
    FCRL3 (Fc Receptor-Like 3 (FCRL3))
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 122-222
    Reaktivität
    • 11
    • 1
    • 1
    Human
    Wirt
    • 7
    • 4
    Kaninchen
    Klonalität
    • 7
    • 4
    Polyklonal
    Konjugat
    • 7
    • 1
    • 1
    • 1
    • 1
    Dieser FCRL3 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 4
    • 4
    • 2
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Fc receptor-like protein 3 protein (122-222AA)
    Isotyp
    IgG
    Top Product
    Discover our top product FCRL3 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FCRL3 (Fc Receptor-Like 3 (FCRL3))
    Andere Bezeichnung
    FCRL3 (FCRL3 Produkte)
    Synonyme
    CD307c antikoerper, FCRH3 antikoerper, IFGP3 antikoerper, IRTA3 antikoerper, SPAP2 antikoerper, fcrh3 antikoerper, ifgp3 antikoerper, irta3 antikoerper, spap2 antikoerper, xfl1.2 antikoerper, Fc receptor like 3 antikoerper, Fc receptor-like 3 L homeolog antikoerper, Fc receptor-like 3 antikoerper, Fc receptor-like 3 S homeolog antikoerper, FCRL3 antikoerper, fcrl3.L antikoerper, fcrl3 antikoerper, fcrl3.S antikoerper
    Hintergrund

    Background: Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).

    Aliases: CD307c antibody, Fc receptor homolog 3 antibody, Fc receptor-like protein 3 antibody, FcR-like protein 3 antibody, FcRH3 antibody, FcRL3 antibody, FCRL3_HUMAN antibody, hIFGP3 antibody, IFGP family protein 3 antibody, IFGP3 antibody, Immune receptor translocation-associated protein 3 antibody, Immunoglobulin superfamily receptor translocation associated protein 3 antibody, IRTA3 antibody, SH2 domain-containing phosphatase anchor protein 2 antibody, SPAP2 antibody

    UniProt
    Q96P31
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