FGG Antikörper (AA 278-437)
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- Target Alle FGG Antikörper anzeigen
- FGG (Fibrinogen gamma Chain (FGG))
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Bindungsspezifität
- AA 278-437
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FGG Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Fibrinogen gamma chain protein (278-437AA)
- Isotyp
- IgG
- Top Product
- Discover our top product FGG Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FGG (Fibrinogen gamma Chain (FGG))
- Andere Bezeichnung
- FGG (FGG Produkte)
- Hintergrund
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Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Aliases: FGG antibody, FIBG_HUMAN antibody, Fibrinogen gamma chain antibody, Fibrinogen gamma polypeptide antibody, fibrinogen gamma-b chain antibody
- UniProt
- P02679
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