FCN1 Antikörper (AA 30-326)

Produktnummer ABIN7152931

Produktdetails anti-FCN1 Antikörper

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Bindungsspezifität: AA 30-326

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FCN1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Ficolin-1 protein (30-326AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FCN1

Target: FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))

Andere Bezeichnung: FCN1 (FCN1 Produkte)

Synonyme: FCNM antikoerper, FCNB antikoerper, FCN2 antikoerper, FCN1 antikoerper, ficolin 1 antikoerper, ficolin (collagen/fibrinogen domain containing) 1 antikoerper, ficolin-1 antikoerper, FCN1 antikoerper, Fcn1 antikoerper, LOC100069029 antikoerper

Hintergrund:

Background: Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

Aliases: Collagen/fibrinogen domain containing protein 1 antibody, Collagen/fibrinogen domain-containing protein 1 antibody, Fcn1 antibody, FCN1_HUMAN antibody, FCNM antibody, ficolin (collagen/fibrinogen domain containing) 1 antibody, Ficolin 1 antibody, Ficolin A antibody, Ficolin alpha antibody, Ficolin-1 antibody, Ficolin-A antibody, Ficolin-alpha antibody, M ficolin antibody, M-ficolin antibody

UniProt: O00602

Pathways: Komplementsystem