FFAR1 Antikörper (AA 143-178)
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- Target Alle FFAR1 Antikörper anzeigen
- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
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Bindungsspezifität
- AA 143-178
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FFAR1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Free fatty acid receptor 1 protein (143-178AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
- Andere Bezeichnung
- FFAR1 (FFAR1 Produkte)
- Synonyme
- FFAR1 antikoerper, GPR40 antikoerper, FFA1R antikoerper, GPCR40 antikoerper, Gpr40 antikoerper, free fatty acid receptor 1 antikoerper, FFAR1 antikoerper, Ffar1 antikoerper
- Hintergrund
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Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
Aliases: FFA1R antibody, FFAR 1 antibody, Ffar1 antibody, FFAR1_HUMAN antibody, Free fatty acid receptor 1 antibody, G protein coupled receptor 40 antibody, G-protein coupled receptor 40 antibody, GPCR40 antibody, GPR 40 antibody, GPR40 antibody
- UniProt
- O14842
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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