FFAR1 Antikörper (AA 143-178) (Biotin)

Produktnummer ABIN7153160

Produktdetails anti-FFAR1 Antikörper (Biotin)

Target: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Bindungsspezifität: AA 143-178

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FFAR1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Free fatty acid receptor 1 protein (143-178AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FFAR1

Target: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Andere Bezeichnung: FFAR1 (FFAR1 Produkte)

Synonyme: FFAR1 antikoerper, GPR40 antikoerper, FFA1R antikoerper, GPCR40 antikoerper, Gpr40 antikoerper, free fatty acid receptor 1 antikoerper, FFAR1 antikoerper, Ffar1 antikoerper

Hintergrund:

Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

Aliases: FFA1R antibody, FFAR 1 antibody, Ffar1 antibody, FFAR1_HUMAN antibody, Free fatty acid receptor 1 antibody, G protein coupled receptor 40 antibody, G-protein coupled receptor 40 antibody, GPCR40 antibody, GPR 40 antibody, GPR40 antibody

UniProt: O14842

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis