FZD1 Antikörper (AA 125-225)

Produktnummer ABIN7153179

Produktdetails anti-FZD1 Antikörper

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Bindungsspezifität: AA 125-225

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Frizzled-10 protein (125-225AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FZD1

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Andere Bezeichnung: FZD1 (Fzd1 Produkte)

Synonyme: CG17697 antikoerper, CG3646 antikoerper, DFZ1 antikoerper, DFz antikoerper, DFz1 antikoerper, Dfz1 antikoerper, Dm Fz1 antikoerper, Dmel\\CG17697 antikoerper, FZ antikoerper, Frz antikoerper, Fz antikoerper, Fz1 antikoerper, frz antikoerper, fz1 antikoerper, fz[[1]] antikoerper, Fz-1 antikoerper, cFz-1 antikoerper, Xfrizzled-1 antikoerper, frizzled1 antikoerper, frz-1 antikoerper, frz1 antikoerper, fzd1-A antikoerper, AW227548 antikoerper, FZ-1 antikoerper, frizzled antikoerper, frizzled class receptor 1 antikoerper, frizzled class receptor 1 L homeolog antikoerper, fz antikoerper, FZD1 antikoerper, Fzd1 antikoerper, fzd1.L antikoerper

Hintergrund:

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Aliases: CD 350 antibody, CD 350 antigen antibody, CD350 antibody, Frizzled (Drosophila) homolog 10 antibody, Frizzled-10 antibody, FZ 10 antibody, Fz-10 antibody, FZ10 antibody, FZD 10 antibody, FZD10 antibody, FZD10_HUMAN antibody, FzE 7 antibody, FzE7 antibody, hFz 10 antibody, hFz10 antibody

UniProt: Q9ULW2

Pathways: WNT Signalweg, Asymmetric Protein Localization