FZD9 Antikörper (AA 23-229)

Produktnummer ABIN7153197

Produktdetails anti-FZD9 Antikörper

Target: FZD9 (Frizzled Family Receptor 9 (FZD9))

Bindungsspezifität: AA 23-229

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Frizzled-9 protein (23-229AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FZD9

Target: FZD9 (Frizzled Family Receptor 9 (FZD9))

Andere Bezeichnung: FZD9 (FZD9 Produkte)

Synonyme: CD349 antikoerper, FZD3 antikoerper, mfz9 antikoerper, Fz-9 antikoerper, cFz-9 antikoerper, fz11 antikoerper, fzd9 antikoerper, fzx antikoerper, hm:zehl0603 antikoerper, zehl0603 antikoerper, zg11 antikoerper, frizzled class receptor 9 antikoerper, frizzled class receptor 9a antikoerper, frizzled class receptor 9b antikoerper, FZD9 antikoerper, Fzd9 antikoerper, fzd9a antikoerper, fzd9b antikoerper

Hintergrund:

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Aliases: CD 349 antibody, CD 349 antigen antibody, CD349 antibody, Frizzled Drosophila homolog of 3 antibody, Frizzled homolog 9 (Drosophila) antibody, Frizzled homolog 9 antibody, Frizzled-9 antibody, Fz 9 antibody, Fz-9 antibody, FZD 3 antibody, Fzd 9 antibody, FZD3 antibody, FZD3-PEN antibody, FZD9 antibody, FZD9_HUMAN antibody, FzE6 antibody, hFz9 antibody, mfz9 antibody, Xfz9 antibody

UniProt: O00144

Pathways: WNT Signalweg