GPR161 Antikörper (AA 1-28)
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- Target Alle GPR161 Antikörper anzeigen
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
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Bindungsspezifität
- AA 1-28
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GPR161 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
- Isotyp
- IgG
- Top Product
- Discover our top product GPR161 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- Andere Bezeichnung
- GPR161 (GPR161 Produkte)
- Synonyme
- RE2 antikoerper, Gm208 antikoerper, Gm208Gpr antikoerper, vl antikoerper, RGD1563245 antikoerper, si:bz20i5.4 antikoerper, si:rp71-20i5.4 antikoerper, G protein-coupled receptor 161 antikoerper, GPR161 antikoerper, Gpr161 antikoerper, gpr161 antikoerper
- Hintergrund
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Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
Aliases: GPR161 antibody, G-protein coupled receptor 161 antibody, G-protein coupled receptor RE2 antibody
- UniProt
- Q8N6U8
- Pathways
- cAMP Metabolic Process
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