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GPR161 Antikörper (AA 1-28)

GPR161 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7153327
  • Target Alle GPR161 Antikörper anzeigen
    GPR161 (G Protein-Coupled Receptor 161 (GPR161))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-28
    Reaktivität
    • 46
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    Human
    Wirt
    • 44
    • 2
    Kaninchen
    Klonalität
    • 44
    • 2
    Polyklonal
    Konjugat
    • 20
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GPR161 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 15
    • 13
    • 13
    • 12
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
    Isotyp
    IgG
    Top Product
    Discover our top product GPR161 Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    GPR161 (G Protein-Coupled Receptor 161 (GPR161))
    Andere Bezeichnung
    GPR161 (GPR161 Produkte)
    Synonyme
    RE2 antikoerper, Gm208 antikoerper, Gm208Gpr antikoerper, vl antikoerper, RGD1563245 antikoerper, si:bz20i5.4 antikoerper, si:rp71-20i5.4 antikoerper, G protein-coupled receptor 161 antikoerper, GPR161 antikoerper, Gpr161 antikoerper, gpr161 antikoerper
    Hintergrund

    Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

    Aliases: GPR161 antibody, G-protein coupled receptor 161 antibody, G-protein coupled receptor RE2 antibody

    UniProt
    Q8N6U8
    Pathways
    cAMP Metabolic Process
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