Gasdermin A Antikörper (AA 64-172)
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- Target Alle Gasdermin A (GSDMA) Antikörper anzeigen
- Gasdermin A (GSDMA)
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Bindungsspezifität
- AA 64-172
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Gasdermin A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Gasdermin-A protein (64-172AA)
- Isotyp
- IgG
- Top Product
- Discover our top product GSDMA Primärantikörper
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anti-Gasdermin A (GSDMA) (AA 21-120) antibody
GSDMA Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Gasdermin A (GSDMA) (AA 66-94), (N-Term) antibodyGSDMA Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB24996 unconjugated
anti-Gasdermin A (GSDMA) (AA 223-272) antibodyGSDMA Reaktivität: Human, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Gasdermin A (GSDMA)
- Andere Bezeichnung
- GSDMA (GSDMA Produkte)
- Synonyme
- BB149167 antikoerper, Gsdm antikoerper, Gsdm1 antikoerper, Gsdma1 antikoerper, H312E antikoerper, GSDM1 antikoerper, GSDM antikoerper, gasdermin A antikoerper, Gsdma antikoerper, GSDMA antikoerper
- Hintergrund
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Background: May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
Aliases: GSDMA antibody, GSDM antibody, GSDM1 antibody, FKSG9Gasdermin-A antibody, Gasdermin-1 antibody
- UniProt
- Q96QA5
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