Mare/Nprl3/C16orf35 Antikörper (AA 349-482) (FITC)

Produktnummer ABIN7153703

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Mare/Nprl3/C16orf35 in . Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Mare/Nprl3/C16orf35 Antikörper (AA 349-482) (FITC) (ABIN7153703)

Target: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mare/Nprl3/C16orf35 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-Mare/Nprl3/C16orf35 Antikörper (FITC)

Bindungsspezifität: AA 349-482

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human GATOR complex protein NPRL3 protein (349-482AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Mare/Nprl3/C16orf35

Target: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Andere Bezeichnung: NPRL3

Hintergrund:

Background: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

Aliases: otein antibody, Alpha-globin regulatory element-containing gene protein antibody, C16ORF35 antibody, CGTHBA antibody, Conserved gene telomeric to alpha globin cluster antibody, HS 40 antibody, MARE antibody, Nitrogen permease regulator 3-like protein antibody, Nitrogen permease regulator-like 3 (S. cerevisiae) antibody, NPR3 antibody, NPRL3 antibody, NPRL3_HUMAN antibody, Protein CGTHBA antibody, RMD11 antibody

UniProt: Q12980