WDR24 Antikörper (AA 1-298) (Biotin)

Produktnummer ABIN7153706

Produktdetails anti-WDR24 Antikörper (Biotin)

Target: WDR24 (WD Repeat Domain 24 (WDR24))

Bindungsspezifität: AA 1-298

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDR24 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human GATOR complex protein WDR24 protein (1-298AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WDR24

Target: WDR24 (WD Repeat Domain 24 (WDR24))

Andere Bezeichnung: WDR24 (WDR24 Produkte)

Synonyme: C16orf21 antikoerper, JFP7 antikoerper, BC037651 antikoerper, wu:fd05f12 antikoerper, zgc:55946 antikoerper, WD repeat domain 24 antikoerper, WD repeat domain 24 L homeolog antikoerper, WDR24 antikoerper, Wdr24 antikoerper, wdr24 antikoerper, wdr24.L antikoerper

Hintergrund:

Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).

Aliases: C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, LA16c-313D11.2 antibody, WD repeat-containing protein 24 antibody, wdr24 antibody, WDR24_HUMAN antibody

UniProt: Q96S15