WDR24 Antikörper (AA 1-298) (FITC)
Kurzübersicht für WDR24 Antikörper (AA 1-298) (FITC) (ABIN7153707)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-298
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human GATOR complex protein WDR24 protein (1-298AA)
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Isotyp
- IgG
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anti-WD Repeat Domain 24 (WDR24) (AA 1-298) antibody
WDR24 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- WDR24 (WD Repeat Domain 24 (WDR24))
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Andere Bezeichnung
- WDR24
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Hintergrund
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Background: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).
Aliases: C16orf21 antibody, DKFZp434F054 antibody, JFP7 antibody, LA16c-313D11.2 antibody, WD repeat-containing protein 24 antibody, wdr24 antibody, WDR24_HUMAN antibody
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UniProt
- Q96S15
Target
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