GEMIN4 Antikörper (AA 741-848) (Biotin)

Produktnummer ABIN7153758

Produktdetails anti-GEMIN4 Antikörper (Biotin)

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Bindungsspezifität: AA 741-848

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GEMIN4 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Gem-associated protein 4 protein (741-848AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GEMIN4

Target: GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))

Andere Bezeichnung: GEMIN4 (GEMIN4 Produkte)

Synonyme: HC56 antikoerper, HCAP1 antikoerper, HHRF-1 antikoerper, p97 antikoerper, 4932415L08Rik antikoerper, AU015359 antikoerper, im:7143815 antikoerper, wu:fc41c09 antikoerper, zgc:110169 antikoerper, GEMIN4 antikoerper, RGD1563715 antikoerper, gem nuclear organelle associated protein 4 antikoerper, gem (nuclear organelle) associated protein 4 antikoerper, GEMIN4 antikoerper, Gemin4 antikoerper, gemin4 antikoerper

Hintergrund:

Background: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

Aliases: GEMIN4 antibody, Gem-associated protein 4 antibody, Gemin-4 antibody, Component of gems 4 antibody, p97 antibody

UniProt: P57678

Pathways: Ribonucleoprotein Complex Subunit Organization