GLRB Antikörper (AA 355-472) (Biotin)
-
- Target Alle GLRB Antikörper anzeigen
- GLRB (Glycine Receptor, beta (GLRB))
-
Bindungsspezifität
- AA 355-472
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser GLRB Antikörper ist konjugiert mit Biotin
-
Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Glycine receptor subunit beta protein (355-472AA)
- Isotyp
- IgG
- Top Product
- Discover our top product GLRB Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- GLRB (Glycine Receptor, beta (GLRB))
- Andere Bezeichnung
- GLRB (GLRB Produkte)
- Synonyme
- HKPX2 antikoerper, glrb antikoerper, MGC145156 antikoerper, AI853901 antikoerper, Glyrb antikoerper, spa antikoerper, spastic antikoerper, glrb2 antikoerper, zgc:101041 antikoerper, glycine receptor beta antikoerper, glycine receptor, beta antikoerper, glycine receptor, beta subunit antikoerper, glycine receptor, beta b antikoerper, GLRB antikoerper, Glrb antikoerper, glrb antikoerper, glrbb antikoerper
- Hintergrund
-
Background: Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).
Aliases: GLRBGlycine receptor subunit beta antibody, Glycine receptor 58 kDa subunit antibody
- UniProt
- P48167
-