GPC1 Antikörper (AA 342-530)
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- Target Alle GPC1 Antikörper anzeigen
- GPC1 (Glypican 1 (GPC1))
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Bindungsspezifität
- AA 342-530
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GPC1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Glypican-1 protein (342-530AA)
- Isotyp
- IgG
- Top Product
- Discover our top product GPC1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GPC1 (Glypican 1 (GPC1))
- Andere Bezeichnung
- GPC1 (GPC1 Produkte)
- Synonyme
- gpc1 antikoerper, zgc:63947 antikoerper, GPC1 antikoerper, Glypican-1 antikoerper, glypican antikoerper, AI462976 antikoerper, HSPG M12 antikoerper, HSPGM12 antikoerper, glypican 1b antikoerper, glypican 1 antikoerper, gpc1b antikoerper, GPC1 antikoerper, gpc1 antikoerper, Gpc1 antikoerper
- Hintergrund
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Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.
Aliases: FLJ38078 antibody, glypican antibody, Glypican proteoglycan 1 antibody, glypican1 antibody, GPC 1 antibody, Gpc1 antibody, GPC1_HUMAN antibody, Secreted glypican-1 antibody
- UniProt
- P35052
- Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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